A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
quote by Francis Crick
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
quote by Francis Crick
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
quote by Francis Crick
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Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
quote by Francis Crick
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The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority.
quote by Francis Crick
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It now seems certain that the amino acid sequence of any protein is determined by the sequence of bases in some region of a particular nucleic acid molecule.
quote by Francis Crick
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
quote by Francis Crick
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Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.
quote by Francis Crick
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That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin.
quote by Edward Lawrie Tatum
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This seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on the genetic map.
quote by Francis Crick
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But sequence comparisons simply can't account for the development of complex biochemical systems any more than Darwin's comparison of simple and complex eyes told him how vision worked.
quote by Michael Behe
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
quote by Francis Crick
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Goin' Under
left home with a friend of mine
gone two years and i don't know why
now i'm happy all the time
i can't think and i'm feelin' fine
girl put me in a situation
going through soft core mutation
think you heard this all before
now you're gonna hear some more
i know a place where dreams get crushed
hopes are smashed but that ain't much
voluntary experimentation
going through soft core mutation
i'm going under
down under where the lights are low
to a place where all the mutants go
doing things i never did before
inside out and coming back for more
little girls with the four red lips
never knew it could be like this
you put me in a situation
goin' through soft core mutation
song performed by by Devo
Submitted by Lucian Velea
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Going Under
Left home with a friend of mine
Gone two years and I dont know why
Now Im happy all the time
I cant think and Im feelin fine
Girl put me in a situation
Going through soft core mutation
Think you heard this all before
Now youre gonna hear some more
I know a place where dreams get crushed
Hopes are smashed but that aint much
Voluntary experimentation
Going through soft core mutation
Im going under
Down under where the lights are low
To a place where all the mutants go
Doing things I never did before
Inside out and coming back for more
Little girls with the four red lips
Never knew it could be like this
You put me in a situation
Goin through soft core mutation
song performed by by Devo
Submitted by Lucian Velea
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How Do You Measure Up?
If you measure yourself by ambition,
There will always be someone more ambitious than you.
If you measure yourself by money,
There is always someone wealthier than you.
If you measure yourself by power,
There is always someone more powerful than you.
If you measure yourself with material things,
There is always someone with more stuff than you.
If you measure yourself by where you are in life,
There is always someone farther down the path than you.
If you measure yourself by appearance,
There is always someone that appears than you.
If you measure yourself by God,
Then we are all the same.
We are all wonderfully and beautifully made.
God is love.
And love has no end.
So in God's heart,
You will always measure up!
poem by Ryan Lee Morris
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There are many methods for predicting the future. For example, you can read horoscopes, tea leaves, tarot cards, or crystal balls. Collectively, these methods are known as 'nutty methods.' Or you can put well-researched facts into sophisticated computer models, more commonly referred to as a complete waste of time.
quote by Scott Adams
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Without ambition one starts nothing. Without work one finishes nothing. The prize will not be sent to you. You have to win it. The man who knows how will always have a job. The man who also knows why will always be his boss. As to methods there may be a million and then some, but principles are few. The man who grasps principles can successfully select his own methods. The man who tries methods, ignoring principles, is sure to have trouble.
Fundamental of Liar Chapter CXXVI: Ruin
Do not ruin a good story
Do not ruin a perfect plan
Do not ruin a flawless lie
Do not ruin a great sacrifice
Do not ruin a hard work
Do not ruin a long trust
Do not ruin a magical moment
Do not ruin a golden opportunity
Do not ruin the current mood
Do not ruin an innocent dream
Do not ruin a sweet memory
Do not ruin a fair game
Do not ruin a mutual agreement
Do not ruin a smiling face
Do not ruin the flowing river
Do not ruin the sequence order
Do not ruin the standard procedure
Do not ruin the prepared show
Do not ruin a complete circle
Do not ruin a final ending
Do not ruin the leisure time
Do not ruin the aiming shot
Do not ruin the hidden purpose
Do not ruin a genius idea
Do not ruin the dead price
Do not ruin a determined mind
poem by Maria Sudibyo
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In 15 years we'll have all the sequence, a list of the genes everyone has in common and those that differ among people. We know only something like a tenth of 1 percent of the sequence at the moment.
quote by Walter Gilbert
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Poetry is not a sequence of experiences, but a sequence of visions.
quote by Ana Blandiana, translated by Dan Costinaş
Submitted by Dan Costinaş
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There are many methods for predicting the future. For example, you can read horoscopes, tea leaves, tarot cards, or crystal balls. Collectively, these methods are known as "nutty methods." Or you can put well-researched facts into sophisticated computer models, more commonly referred to as "a complete waste of time."
Scott Adams in The Dilbert Future
Submitted by Lucian Velea
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